First find where your boat feels happy. You know,....that sweet spot that she likes to cruise in. Trim her up, trim her down, adjust your Rpm's, until she lays down comfortable and is performing without any laboring. You'll know it when it feels right. The boat will just hum along.
After knowing how she likes to ride, which changes with the conditions, then you can find out what your burning. One way it to top of your tank. Then take a nice long cruise, the longer the better. The longer you cruise for the more accurate your numbers will be. Try to take a run where you don't have to change speed or slow to a no wake zone. That will effect the numbers. Take notes while your under way. Once back at the fuel dock note your mileage traveled, (either from your charts or more accuratly, a GPS). Top off your tank and note the gallons replaced. Now you have two numbers to your equation, Fuel burned, and miles traveled.
Keep in mind that this will change depending many variables. Wind, currents, wave heights, etc... All the more reason to do this test in different conditions.
Or you could just install a floScan..
